Association of allostatic load with brain structure and cognitive ability in later life
نویسندگان
چکیده
منابع مشابه
Association of allostatic load with brain structure and cognitive ability in later life
Allostatic load (AL) has been proposed as a general framework for understanding the cumulative effects of life stress on individuals. Despite growing interest in AL, limited research has been conducted on aging samples. We consider the association of AL (operationalized by a range of inflammatory, cardiovascular, and metabolic measures) with a range of brain volume measurements and cognitive ab...
متن کاملHistory of socioeconomic disadvantage and allostatic load in later life.
There is a growing interest in understanding how the experience of socioeconomic status (SES) adversity across the life course may accumulate to negatively affect the functioning of biological regulatory systems important to functioning and health in later adulthood. The goal of the present analyses was to examine whether greater life course SES adversity experience would be associated with hig...
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OBJECTIVE Living a purposeful life is associated with better mental and physical health, including longevity. Accumulating evidence shows that these associations might be explained by the association between life purpose and regulation of physiological systems involved in the stress response. The aim of this study was to investigate the prospective associations between life purpose and allostat...
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110 words Main text: 2501 Tables: 1 Figures: 1 References: 34 Supplementary material: 1 supplementary table and 1 supplementary figure not peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission. The copyright holder for this preprint (which was . http://dx.doi.org/10.1101/183525 doi: bioRxiv preprint first posted online Sep. 1, 2017;
متن کاملCoupled changes in hippocampal structure and cognitive ability in later life
Introduction The hippocampus plays an important role in cognitive abilities which often decline with advancing age. Methods In a longitudinal study of community-dwelling adults, we investigated whether there were coupled changes in hippocampal structure and verbal memory, working memory, and processing speed between the ages of 73 (N = 655) and 76 years (N = 469). Hippocampal structure was in...
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ژورنال
عنوان ژورنال: Neurobiology of Aging
سال: 2015
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2014.12.020